Lot numbers can be found on the outside label of a product:
3-Chloro-4,5-dihydroxybenzaldehyde
-
CAS No. 34098-18-5
- Cat. No. CS-0308445
- Purity≥97%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 34098-18-5
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 34098-18-5
- Cat. No. CS-0308445
- Purity ≥97%
- MDL No. None
- Storage 4°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₅ClO₃
- Molecular Weight 172.57
- Synonym(s) 5-chloroprotocatechualdehyde
- SMILES O=CC1=CC(O)=C(O)C(Cl)=C1
Description
3-Chloro-4,5-dihydroxybenzaldehyde features a chlorinated aromatic core with adjacent hydroxyl groups, enabling facile derivatization in synthetic routes. The aldehyde functionality provides a reactive handle for conjugation, while the ortho-diol system enhances metal chelation potential. This compound serves as a key building block in bioactive molecule synthesis and fluorescent probe development.
Application
3-Chloro-4,5-dihydroxybenzaldehyde serves as a versatile building block in medicinal chemistry and natural product synthesis, enabling efficient access to substituted catechol scaffolds. Its ortho-dihydroxy functionality supports metal complexation and oxidative coupling, while the aldehyde group facilitates reductive amination, imine formation, and conjugate addition reactions. The chloro substituent provides a handle for further functionalization via palladium-catalyzed cross-coupling. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step syntheses requiring selective reactivity and functional group compatibility.
Synthesis
-
Route1
-
In-stock
19463-48-0 - ~96%
-
In-stock
34098-18-5
References
-
Hua, Duy H.; Huang, Xiaodong; Chen, Yi; Battina, Srinivas K.; Tamura, Masafumi; Noh, Sang K.; Koo, Sung I.; Namatame, Ichiji; Tomoda, Hiroshi; Perchellet, Elisabeth M.; Perchellet, Jean-Pierre Journal of Organic Chemistry, 2004 , vol. 69, # 18 p. 6065 - 6078
-
-
Route2
-
100-52-7 - ~94%
-
In-stock
34098-18-5
References
-
Kansas State University Research Foundation Patent: US6727277 B1, 2004 ; Location in patent: Page/Page column 32 ;
-
-
Route3
-
121-33-5 - ~%
-
In-stock
34098-18-5
References
-
Journal of Organic Chemistry, , vol. 69, # 18 p. 6065 - 6078
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 57.53
- LogP 1.5637
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 3-Chloro-4,5-dihydroxybenzaldehyde sigma3-Chloro-4,5-dihydroxybenzaldehyde manufacturer3-Chloro-4,5-dihydroxybenzaldehyde price3-Chloro-4,5-dihydroxybenzaldehyde structure3-Chloro-4,5-dihydroxybenzaldehyde SDSbuy 3-Chloro-4,5-dihydroxybenzaldehyde3-Chloro-4,5-dihydroxybenzaldehyde supplier3-Chloro-4,5-dihydroxybenzaldehyde uses3-Chloro-4,5-dihydroxybenzaldehyde molecular weightprice of 3-Chloro-4,5-dihydroxybenzaldehyde3-Chloro-4,5-dihydroxybenzaldehyde chemical name formula of 3-Chloro-4,5-dihydroxybenzaldehyde