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Structure of 3413-28-3
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4-(4-Fluorophenoxy)piperidine features a fluorinated aromatic ring linked to a piperidine core, delivering enhanced metabolic stability and improved membrane permeability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for CNS-targeted therapeutics.
4-(4-Fluorophenoxy)piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its fluorinated aryl ether moiety enhances metabolic stability and membrane permeability, while the piperidine core provides a basic nitrogen for salt formation and target engagement. The compound exhibits good bench stability and is compatible with common synthetic workflows, facilitating purification and integration into lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: