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Structure of 341556-25-0
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1-(6-Bromopyridin-2-yl)propan-1-one features a brominated pyridine ring linked to a ketone-functionalized propyl chain, enabling direct incorporation into cross-coupling reactions. The electron-deficient pyridine moiety enhances reactivity in palladium-catalyzed transformations, while the bench-stable ketone group supports straightforward derivatization. This compound serves as a key building block for functionalized heterocycles in medicinal chemistry and materials science.
1-(6-Bromopyridin-2-yl)propan-1-one serves as a versatile building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The bromine atom facilitates palladium-catalyzed coupling with boronic acids, esters, and other nucleophiles under standard conditions. Its ketone functionality provides additional handle for further functionalization, including enolate chemistry and reductive amination. Bench-stable and readily purified by flash chromatography, it supports scalable synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: