3′-Deoxythymidine

Name: 3′-Deoxythymidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 3416-05-5
Cat. No. CS-W013027
Purity≥98%
MDL No.MFCD00010570

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 3416-05-5

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Description

3′-Deoxythymidine is a nucleoside analog featuring a modified sugar moiety that lacks the 3′-hydroxyl group, rendering it incapable of forming phosphodiester bonds in DNA chains. This structural feature enables its use as a chain terminator in nucleic acid synthesis studies and antiviral research, particularly in investigating reverse transcriptase activity. The compound exhibits stability under standard laboratory conditions and integrates readily into oligonucleotide sequences for mechanistic probing.

Application

3′-Deoxythymidine serves as a valuable nucleoside building block in the synthesis of antiviral agents and oligonucleotide analogs. Its modified sugar moiety enhances metabolic stability while retaining compatibility with standard phosphoramidite coupling protocols. The 3′-deoxy configuration prevents chain elongation, making it useful for controlled oligonucleotide synthesis and mechanistic studies of polymerase activity.

General Information

CAS No. 3416-05-5
Cat. No. CS-W013027
Purity ≥98%
MDL No. MFCD00010570
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₄N₂O₄
Molecular Weight 226.23
Synonym(s) 2′,3′-Dideoxythymidine; ddThd
SMILES O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](CO)CC2

Computational Chemistry Data

TPSA 84.32
LogP -0.48508
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Life Science Nucleosides & Nucleotides Other Protective Nucleosides

Chemical Biology Nucleic Acid Chemistry Protected Nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

Biochemistry Biochemicals and Reagents Pharmaceutical Research Reagents Antiviral Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Pharmaceutical Research Reagents Antiviral Research Reagents

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3′-Deoxythymidine

CAS No. 3416-05-5

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