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Structure of 3416-18-0
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5-Hydroxyoxindole features a hydroxyl group at the C5 position of the oxindole core, enhancing its polarity and enabling direct participation in hydrogen bonding. This structural motif supports integration into bioactive molecule scaffolds, particularly in kinase inhibitor design and fluorescent probe development. The compound exhibits bench-stable handling characteristics under standard conditions.
5-Hydroxyoxindole serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard functional group manipulations. Its phenolic hydroxyl and carbonyl groups provide orthogonal reactivity for derivatization, while the oxindole core offers structural rigidity and hydrogen-bonding capacity relevant to target binding. The compound exhibits good bench stability and facilitates efficient purification via recrystallization or chromatography, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: