5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine

Name: 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine
Brand: ChemScene
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CAS No. 34167-66-3
Cat. No. CS-0138089
Purity≥96%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine|CS-0138089

Structure of 34167-66-3

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Description

This tetrahydroimidazo[1,2-a]pyridine scaffold delivers a rigid, nitrogen-rich heterocyclic core ideal for medicinal chemistry applications. Featuring enhanced solubility and metabolic stability, it integrates efficiently into complex molecular architectures. The fused ring system provides defined spatial orientation, supporting precise ligand-receptor interactions in drug discovery.

Application

5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, offering a rigid, nitrogen-rich scaffold with well-documented utility in the synthesis of bioactive molecules. Its stability and compatibility with standard functional group transformations enable efficient access to complex pharmaceutical intermediates. The compound functions effectively in coupling reactions and as a core motif in CNS-targeted drug discovery programs.

General Information

CAS No. 34167-66-3
Cat. No. CS-0138089
Purity ≥96%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight 122.17
Synonym(s) Imidazo[1,2-a]pyridine, 5,6,7,8-tetrahydro- (8CI,9CI)
SMILES C12=NC=CN1CCCC2

Computational Chemistry Data

TPSA 17.82
LogP 1.2194
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine

CAS No. 34167-66-3

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