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2-Methyl-2H-indazole-3-carbaldehyde

  • CAS No. 34252-54-5

  • Cat. No. CS-0101167
  • Molecule weight160.17
  • Purity≥97%
  • MDL No.MFCD00839530

*For research and further manufacturing use only, not for direct human use.

2-Methyl-2H-indazole-3-carbaldehyde|CS-0101167

Structure of 34252-54-5

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General Information

  • CAS No. 34252-54-5
  • Cat. No. CS-0101167
  • Purity ≥97%
  • MDL No. MFCD00839530
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O
  • Molecular Weight 160.17
  • Synonym(s) 2H-indazole-3-carboxaldehyde, 2-methyl-
  • SMILES O=CC1=C2C=CC=CC2=NN1C

Description

2-Methyl-2H-indazole-3-carbaldehyde features a fused bicyclic indazole core with a methyl group at the 2-position and a formyl substituent at the 3-position. This electron-deficient aldehyde integrates readily into heterocyclic scaffolds, offering high reactivity in coupling reactions and serving as a key building block for bioactive molecule synthesis.

Application

2-Methyl-2H-indazole-3-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to indazole-based scaffolds through standard condensation and coupling reactions. Its aldehyde functionality facilitates facile derivatization via reductive amination, Grignard additions, and Wittig-type transformations, while the methyl group enhances metabolic stability. The compound exhibits good bench stability and is readily purified by column chromatography, making it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.89
  • LogP   1.3858
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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