3,5-Dibromo-2,6-dimethylpyridine

Name: 3,5-Dibromo-2,6-dimethylpyridine
Brand: ChemScene
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CAS No. 3430-34-0
Cat. No. CS-W006812
Purity≥98%
MDL No.MFCD00234282

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3,5-Dibromo-2,6-dimethylpyridine|CS-W006812

Structure of 3430-34-0

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Description

3,5-Dibromo-2,6-dimethylpyridine features two bromine atoms at the 3 and 5 positions flanking a central nitrogen atom, with methyl groups at the 2 and 6 positions. This sterically hindered architecture enhances stability under standard conditions while enabling selective coupling reactions in cross-coupling methodologies. The electron-deficient pyridine core facilitates transition metal-catalyzed transformations, making it a robust scaffold for synthesizing functionalized heterocycles.

Application

3,5-Dibromo-2,6-dimethylpyridine serves as a versatile building block in synthetic organic chemistry, enabling the construction of substituted pyridine scaffolds via palladium-catalyzed cross-coupling reactions. The bromo groups exhibit high reactivity in Suzuki, Stille, and Negishi couplings, while the methyl substituents enhance stability and facilitate purification. Its ortho-directed substitution pattern supports regioselective functionalization, making it valuable for medicinal chemistry and materials science applications requiring controlled molecular architecture.

General Information

CAS No. 3430-34-0
Cat. No. CS-W006812
Purity ≥98%
MDL No. MFCD00234282
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇Br₂N
Molecular Weight 264.95
Synonym(s) 2-Chloro-5-Methyl-pyriMidin-4-ylaMine
SMILES CC1=NC(=C(C=C1Br)Br)C

Computational Chemistry Data

TPSA 12.89
LogP 3.22344
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3,5-Dibromo-2,6-dimethylpyridine

CAS No. 3430-34-0

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