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Structure of 343569-02-8
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4-Iodo-1,2-dimethyl-1H-imidazole is a bench-stable, moisture-tolerant heterocyclic building block featuring a reactive iodine handle at the 4-position. The electron-deficient imidazole core pairs effectively with palladium catalysts in cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation under standard conditions. This reagent streamlines access to functionalized imidazoles for medicinal chemistry and materials applications.
4-Iodo-1,2-dimethyl-1H-imidazole serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, particularly in Suzuki-Miyaura and Stille couplings. The iodide moiety enables efficient C–C bond formation under mild conditions, while the N-methylated imidazole core provides enhanced bench stability and solubility. Its defined regiochemistry and functional group tolerance make it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: