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CS-W001157 4
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1,2-Didecanoyl PC

  • CAS No. 3436-44-0

  • Cat. No. CS-0138073
  • Molecule weight565.72
  • Purity≥98%
  • MDL No.MFCD00063538

*For research and further manufacturing use only, not for direct human use.

1,2-Didecanoyl PC|CS-0138073

Structure of 3436-44-0

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General Information

  • CAS No. 3436-44-0
  • Cat. No. CS-0138073
  • Purity ≥98%
  • MDL No. MFCD00063538
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₅₆NO₈P
  • Molecular Weight 565.72
  • Synonym(s) 1,2-Didecanoyl-sn-glycero-3-phosphocholine
  • SMILES C[N+](C)(C)CCOP(OC[C@H](OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)([O-])=O

Description

Synthesizing membrane bilayers with reduced hydrophobic thickness, 10:0 PC (CAS 3436-44-0) modulates lateral lipid packing and enhances fusogenicity in artificial vesicle systems.

Application

10:0 PC (CAS 3436-44-0) serves as a critical internal standard for quantifying lipid metabolites in metabolic profiling workflows employing hydrophilic interaction liquid chromatography, enabling precise detection of subtle lipid shifts across biological samples. It also forms stable bilayers. Researchers leverage this setup to reconstitute Vpu and probe the lipid-induced conformational dynamics of the 27-residue Cry4Ba-α7 peptide within defined phospholipid membranes.

Synthesis

  • Route1

    References

    • Koegl,F. et al. Recueil des Travaux Chimiques des Pays-Bas, 1960 , vol. 79, p. 661 - 674

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H331-H336-H351-H361-H372
Precautionary Statements : P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   111.19
  • LogP   5.9306
  • H_Acceptors   8
  • H_Donors   0
  • Rotatable_Bonds   26

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