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Structure of 343866-99-9
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2-Ethynyl-1-fluoro-4-nitrobenzene features a strategically positioned ethynyl group flanked by electron-withdrawing fluoro and nitro substituents, enabling efficient copper-catalyzed coupling reactions. This ortho-fluorinated aryl alkyne exhibits enhanced reactivity in click chemistry applications while maintaining bench-stable handling characteristics under standard conditions.
2-Ethynyl-1-fluoro-4-nitrobenzene serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to conjugated aryl architectures. The fluorine and nitro groups provide orthogonal reactivity for downstream functionalization, while the terminal alkyne facilitates Sonogashira and click-type transformations. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: