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CS-W001157 4
Total: USD 88.00

Dibutyldichlorosilane

  • CAS No. 3449-28-3

  • Cat. No. CS-0168454
  • Molecule weight213.22
  • Purity≥95%
  • MDL No.MFCD00053202

*For research and further manufacturing use only, not for direct human use.

Dibutyldichlorosilane|CS-0168454

Structure of 3449-28-3

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General Information

  • CAS No. 3449-28-3
  • Cat. No. CS-0168454
  • Purity ≥95%
  • MDL No. MFCD00053202
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈Cl₂Si
  • Molecular Weight 213.22
  • Synonym(s) ibutyl(dichloro)silane
  • SMILES Cl[Si](CCCC)(CCCC)Cl

Description

Dibutyldichlorosilane serves as a robust silylating agent for hydroxyl groups, offering high reactivity under mild conditions. This moisture-tolerant reagent enables efficient protection of alcohols in complex molecular architectures, facilitating downstream synthetic manipulations without decomposition.

Application

Dibutyldichlorosilane serves as a reliable reagent for the selective protection of alcohols and thiols under mild conditions, enabling efficient formation of silyl ethers and thiosilyl derivatives. Its bench-stable nature, ease of handling, and compatibility with diverse functional groups make it well-suited for complex molecule synthesis, particularly in medicinal chemistry and natural product applications where orthogonal protection strategies are required.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2987
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.5064
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   6

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