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Structure of 346603-63-2
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Methyl 2-methyl-3-(trifluoromethyl)benzoate features a trifluoromethyl group that imparts enhanced electron-withdrawal and metabolic stability, while the methyl ester enables straightforward derivatization. This aromatic carboxylate integrates readily into synthetic routes requiring sterically accessible, electron-deficient benzoyl equivalents under standard conditions.
Methyl 2-methyl-3-(trifluoromethyl)benzoate serves as a versatile building block in medicinal chemistry and synthetic organic research. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the methyl ester enables straightforward derivatization via hydrolysis or nucleophilic substitution. The ortho-methyl and meta-trifluoromethyl substituents provide steric and electronic modulation, facilitating downstream functionalization in heterocycle synthesis and transition-metal-catalyzed coupling reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: