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Structure of 34667-88-4
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2-Fluoro-4-nitrobenzonitrile features a trifunctional aromatic core with electron-withdrawing fluorine, nitro, and nitrile groups positioned for orthogonal reactivity. This configuration enables selective coupling in cross-coupling protocols and facilitates integration into bioactive scaffolds. The compound exhibits enhanced stability under standard conditions and compatibility with diverse reaction environments.
2-Fluoro-4-nitrobenzonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling efficient construction of heterocyclic scaffolds via nucleophilic aromatic substitution. The ortho-fluorine facilitates selective displacement under mild conditions, while the nitro and cyano groups provide orthogonal reactivity for downstream functionalization. Bench-stable and readily purified by recrystallization, it supports scalable synthesis in multi-step routes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: