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Structure of 347187-30-8
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Thieno[3,2-b]pyridine-2-carboxylic acid features a fused heterocyclic core combining thiophene and pyridine units, delivering enhanced electron-withdrawing character. The carboxylic acid group enables direct conjugation and facilitates derivatization via amide or ester linkages. This scaffold exhibits high thermal stability and favorable solubility in polar organic solvents, making it suitable for synthetic applications in pharmaceutical intermediates and functional materials.
Thieno[3,2-b]pyridine-2-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amide coupling and derivatization protocols. Its rigid fused structure imparts metabolic stability and favorable binding interactions, while the carboxylic acid group facilitates conjugation with amines, alcohols, or nucleophiles under mild conditions. The compound exhibits good bench stability and is compatible with common purification methods, making it suitable for high-throughput synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: