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CS-W001157 4
Total: USD 88.00

Ethyl 4-chloro-2-morpholinopyrimidine-5-carboxylate

  • CAS No. 34750-23-7

  • Cat. No. CS-0451472
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-chloro-2-morpholinopyrimidine-5-carboxylate|CS-0451472

Structure of 34750-23-7

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General Information

  • CAS No. 34750-23-7
  • Cat. No. CS-0451472
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄ClN₃O₃
  • Molecular Weight 271.70
  • Synonym(s) ethyl 4-chloro-2-(morpholin-4-yl)pyrimidine-5-carboxylate
  • SMILES CCOC(=O)C1=CN=C(N=C1Cl)N2CCOCC2

Synthesis

  • Route1
    • Ethyl 4-hydroxy-2-morpholinopyrimidine-5-carboxylate|CS-0207821
      25693-41-8
    • ~94%
    • Ethyl 4-chloro-2-morpholinopyrimidine-5-carboxylate|CS-0451472
      34750-23-7

    References

    • WARNER-LAMBERT COMPANY LLC Patent: WO2005/42519 A1, 2005 ; Location in patent: Page/Page column 41 ; WO 2005/042519 A1
  • Route2

    References

    • WO2012/3264 A1, ; WO 2012/003264 A1
  • Route3
    • Morpholine-4-carboximidamide|CS-0464327
      17238-66-3
    • ~%
    • Ethyl 4-chloro-2-morpholinopyrimidine-5-carboxylate|CS-0451472
      34750-23-7

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 21 p. 6756 - 6761

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.55
  • LogP   1.1433
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   3

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