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Structure of 34784-06-0
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7-Chloroisoquinoline is a bench-stable, electron-deficient heterocycle featuring a chlorine substituent at the 7-position. This configuration enhances its reactivity in transition-metal-catalyzed couplings and facilitates integration into pharmaceutical scaffolds. The para-chloro group serves as a versatile handle for further functionalization.
7-Chloroisoquinoline serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling direct functionalization at the C-1 and C-3 positions via Pd-catalyzed cross-coupling. Its electron-deficient aromatic core enhances reactivity in nucleophilic substitution and transition-metal-mediated transformations, while maintaining bench stability and ease of purification. Functions as a key scaffold for heterocyclic APIs and advanced intermediates in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P362-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: