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Structure of 34803-68-4
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1-(2-Pyrazinyl)-piperazine features a pyrazinyl group directly fused to a piperazine core, creating a rigid, electron-deficient heterocyclic scaffold. This configuration enhances binding affinity in kinase inhibitors and other bioactive molecules. The compound serves as a key building block in medicinal chemistry, integrating readily into diverse pharmacophores via its nucleophilic nitrogen atoms.
1-(2-Pyrazinyl)-piperazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling reactions. Its pyrazine core provides enhanced metabolic stability and favorable physicochemical properties, while the piperazine moiety offers solubility and hydrogen-bonding capacity. The compound exhibits bench stability and facilitates straightforward functionalization, making it well-suited for lead optimization campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: