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Structure of 3484-35-3
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5-Methylindolin-2-one is a bench-stable, electron-rich heterocycle featuring a fused indoline core with a methyl substituent at the 5-position. This structural motif delivers enhanced solubility and stability in polar solvents, enabling efficient integration into synthetic routes for bioactive molecules. The carbonyl group facilitates nucleophilic addition and cyclization reactions under mild conditions.
5-Methylindolin-2-one serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization at the C3 and C5 positions. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient derivatization. The ketone functionality supports nucleophilic addition and reduction, while the indolinone core provides structural rigidity and hydrogen-bonding potential relevant to target binding.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: