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Structure of 34883-46-0
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1-Iodo-2-phenoxybenzene is a versatile aryl iodide featuring a phenoxy substituent that enhances solubility and modulates reactivity. This bench-stable compound facilitates efficient cross-coupling transformations, particularly in Suzuki-Miyaura and Stille reactions, where the iodine moiety serves as a high-activity coupling handle. The ortho-phenoxy group provides electronic stabilization and minimizes side reactions, enabling reliable functionalization under standard conditions.
1-Iodo-2-phenoxybenzene serves as a versatile aryl halide building block for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The phenoxy substituent provides enhanced stability and facilitates purification, while the iodine moiety ensures high reactivity in transition metal-mediated transformations. This compound functions reliably in the synthesis of biaryl scaffolds relevant to pharmaceutical and materials chemistry.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: