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CS-W001157 4
Total: USD 88.00

Biotin NHS

  • CAS No. 35013-72-0

  • Cat. No. CS-5714
  • Molecule weight341.38
  • Purity≥95%
  • MDL No.MFCD00078531

*For research and further manufacturing use only, not for direct human use.

Biotin NHS|CS-5714

Structure of 35013-72-0

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General Information

  • CAS No. 35013-72-0
  • Cat. No. CS-5714
  • Purity ≥95%
  • MDL No. MFCD00078531
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉N₃O₅S
  • Molecular Weight 341.38
  • Synonym(s) Biotin N-hydroxysuccinimide ester; NHS-Biotin
  • SMILES O=C(ON1C(CCC1=O)=O)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O

Description

Conjugating primary amines via amide bond formation, (+)-Biotin N-hydroxysuccinimide ester (CAS 35013-72-0) enables site-specific labeling of biomolecules in aqueous buffers at physiological pH.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 129, # 45 p. 13987 - 13996
  • Route2

    References

    • WO2007/131286 A1, ; Page/Page column 70 ;
  • Route3
    • In-stock
      HOSU Amino acid impurity|CS-1733141
      6066-82-6
    • null|null
      101187-31-9
    • ~88%
    • In-stock
      Biotin NHS|CS-5714
      35013-72-0

    References

    • Journal of Medicinal Chemistry, , vol. 27, # 11 p. 1406 - 1410

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   104.81
  • LogP   0.3194
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   6

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