Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Chloro-2-fluorobenzenesulfonyl chloride

  • CAS No. 351003-48-0

  • Cat. No. CS-W008244
  • Purity≥95%
  • MDL No.MFCD03094234

*For research and further manufacturing use only, not for direct human use.

3-Chloro-2-fluorobenzenesulfonyl chloride|CS-W008244

Structure of 351003-48-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 351003-48-0
  • Cat. No. CS-W008244
  • Purity ≥95%
  • MDL No. MFCD03094234
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Cl₂FO₂S
  • Molecular Weight 229.06
  • Synonym(s) Benzenesulfonyl chloride, 3-chloro-2-fluoro-; 3-Chloro-2-fluorobenzenesulfonyl chloride
  • SMILES O=S(C1=CC=CC(Cl)=C1F)(Cl)=O

Description

3-Chloro-2-fluorobenzenesulfonyl chloride features a sulfonyl chloride group flanked by ortho-chloro and ortho-fluoro substituents, enabling selective sulfonamide formation. This electron-deficient aromatic system enhances reactivity in nucleophilic substitution while maintaining stability under standard bench conditions.

Application

3-Chloro-2-fluorobenzenesulfonyl chloride serves as a versatile electrophilic sulfonylating agent, enabling efficient introduction of the sulfonyl group into aromatic and heterocyclic systems. Its reactivity is enhanced by the orthogonal electron-withdrawing effects of the 3-chloro and 2-fluoro substituents, facilitating selective transformations in complex molecule synthesis. The compound exhibits good bench stability and compatibility with common protecting groups, making it well-suited for use in medicinal chemistry campaigns requiring functional group diversity and predictable reactivity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   34.14
  • LogP   2.4066
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 351003-48-0 sigma351003-48-0 manufacturer351003-48-0 price351003-48-0 structure351003-48-0 SDSbuy 351003-48-0351003-48-0 supplier351003-48-0 uses351003-48-0 molecular weightprice of 351003-48-0351003-48-0 chemical name formula of 351003-48-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label