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CS-W001157 4
Total: USD 88.00

(3-Carbamoylphenyl)boronic acid

  • CAS No. 351422-73-6

  • Cat. No. CS-W017897
  • Purity≥95%
  • MDL No.MFCD03411948
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(3-Carbamoylphenyl)boronic acid|CS-W017897

Structure of 351422-73-6

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Description

(3-Carbamoylphenyl)boronic acid features a boronic acid group attached to a phenyl ring bearing a carbamoyl substituent at the meta position. This combination enables direct incorporation into Suzuki-Miyaura coupling reactions, where the electron-deficient aryl moiety enhances reactivity. The functionalized scaffold supports efficient synthesis of bioactive aryl amides and pharmaceutical intermediates under mild conditions.

Application

(3-Carbamoylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient access to biaryl scaffolds with retained functional group compatibility. Its boronic acid moiety facilitates reliable coupling under mild conditions, while the ortho-carbamoyl group offers enhanced solubility and stability, simplifying purification and improving handling for medicinal chemistry and process development workflows.

General Information

  • CAS No. 351422-73-6
  • Cat. No. CS-W017897
  • Purity ≥95%
  • MDL No. MFCD03411948
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BNO₃
  • Molecular Weight 164.95
  • Synonym(s) BENZAMIDE-3-BORONIC ACID
  • SMILES NC(C1=CC(B(O)O)=CC=C1)=O

Computational Chemistry Data

  • TPSA   83.55
  • LogP   -1.5347
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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