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CS-W001157 4
Total: USD 88.00

4,6-Dimethyl-2-methylsulfonylpyrimidine

  • CAS No. 35144-22-0

  • Cat. No. CS-W003098
  • Purity≥98%
  • MDL No.MFCD03788286

*For research and further manufacturing use only, not for direct human use.

4,6-Dimethyl-2-methylsulfonylpyrimidine|CS-W003098

Structure of 35144-22-0

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General Information

  • CAS No. 35144-22-0
  • Cat. No. CS-W003098
  • Purity ≥98%
  • MDL No. MFCD03788286
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂O₂S
  • Molecular Weight 186.24
  • Synonym(s) 2-METHANESULFONYL-4,6-DIMETHYL-PYRIMIDINE
  • SMILES CC1=CC(C)=NC(S(C)(=O)=O)=N1

Description

4,6-Dimethyl-2-methylsulfonylpyrimidine features a pyrimidine core functionalized with two methyl groups at positions 4 and 6, and a methylsulfonyl group at position 2. This electron-deficient heterocycle serves as a stable, bench-compatible scaffold for constructing bioactive molecules in medicinal chemistry and agrochemical research.

Application

4,6-Dimethyl-2-methylsulfonylpyrimidine serves as a versatile pyrimidine scaffold for medicinal chemistry and materials science applications. The methylsulfonyl group enhances solubility and metabolic stability, while the 4,6-dimethyl substitution provides steric protection and electronic modulation. This compound facilitates nucleophilic substitution reactions and functions as a key building block in the synthesis of kinase inhibitors and functionalized heterocycles. Its bench-stable nature and compatibility with standard coupling protocols support efficient route development and scale-up.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.92
  • LogP   0.49694
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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