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Structure of 352-68-1
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p-(Trifluoromethylthio)toluene features a para-substituted trifluoromethylthio group that imparts strong electron-withdrawing character and enhanced metabolic stability. This bench-stable arylthio derivative enables efficient coupling reactions in synthetic organic chemistry, particularly in cross-coupling and electrophilic functionalization processes.
p-(Trifluoromethylthio)toluene serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering a robust trifluoromethylthio group ortho to a methyl functionality. Its stability under standard reaction conditions enables reliable use in cross-coupling, electrophilic substitution, and functional group interconversions. The molecule facilitates access to fluorinated aromatic scaffolds with enhanced metabolic stability and lipophilicity, commonly found in bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: