Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Methoxy-1H-indazole

  • CAS No. 3522-07-4

  • Cat. No. CS-D1536
  • Purity≥97%
  • MDL No.MFCD09261132

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-1H-indazole|CS-D1536

Structure of 3522-07-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 3522-07-4
  • Cat. No. CS-D1536
  • Purity ≥97%
  • MDL No. MFCD09261132
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂O
  • Molecular Weight 148.16
  • Synonym(s) 6-Methoxyindazole; 6-Methoxy-2H-indazole
  • SMILES COC1=CC2=C(C=C1)C=NN2

Description

6-Methoxy-1H-indazole is a bench-stable heterocyclic scaffold featuring a methoxy group at the 6-position, enhancing solubility and modulating electronic properties. This electron-rich indazole core integrates readily into bioactive molecule design, offering favorable metabolic stability and compatibility with diverse coupling reactions.

Application

6-Methoxy-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, offering enhanced solubility and metabolic stability over unsubstituted indazoles. The methoxy group at the 6-position provides a handle for further functionalization via cross-coupling or electrophilic substitution, while maintaining compatibility with standard synthetic protocols. Its bench-stable nature and predictable reactivity make it well-suited for modular synthesis of kinase inhibitors and other bioactive scaffolds.

Synthesis

  • Route1

    References

    • Tung, Yen-Shih; Coumar, Mohane Selvaraj; Wu, Yu-Shan; Shiao, Hui-Yi; Chang, Jang-Yang; Liou, Jing-Ping; Shukla, Paritosh; Chang, Chun-Wei; Chang, Chi-Yen; Kuo, Ching-Chuan; Yeh, Teng-Kuang; Lin, Chin-Yu; Wu, Jian-Sung; Wu, Su-Ying; Liao, Chun-Chen; Hsieh, Hsing-Pang Journal of Medicinal Chemistry, 2011 , vol. 54, # 8 p. 3076 - 3080
  • Route2
    • In-stock
      6-Hydroxyindazole|CS-W001119
      23244-88-4
    • null|null
      74-88-4
    • ~79%
    • In-stock
      6-Methoxy-1H-indazole|CS-D1536
      3522-07-4

    References

    • Vernekar, Sanjeev Kumar V.; Hallaq, Hasan Y.; Clarkson, Guy; Thompson, Andrew J.; Silvestr, Linda; Lummis, Sarah C. R.; Lochner, Martin Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2324 - 2328
  • Route3
    • null|null
      343773-70-6
    • ~%
    • In-stock
      6-Methoxy-1H-indazole|CS-D1536
      3522-07-4

    References

    • Liebigs Annalen der Chemie, , # 6 p. 908 - 927

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.91
  • LogP   1.5715
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Methoxy-1H-indazole sigma6-Methoxy-1H-indazole manufacturer6-Methoxy-1H-indazole price6-Methoxy-1H-indazole structure6-Methoxy-1H-indazole SDSbuy 6-Methoxy-1H-indazole6-Methoxy-1H-indazole supplier6-Methoxy-1H-indazole uses6-Methoxy-1H-indazole molecular weightprice of 6-Methoxy-1H-indazole6-Methoxy-1H-indazole chemical name formula of 6-Methoxy-1H-indazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label