(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(pyridin-3-yl)phenyl)propanoic acid

Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(pyridin-3-yl)phenyl)propanoic acid
Brand: ChemScene
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CAS No. 352525-25-8
Cat. No. CS-0169354
Purity≥97%
MDL No.None

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(pyridin-3-yl)phenyl)propanoic acid|CS-0169354

Structure of 352525-25-8

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Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(pyridin-3-yl)phenyl)propanoic acid features a chiral α-amino acid core with a fluorenylmethoxycarbonyl (Fmoc) protecting group, enabling direct use in solid-phase peptide synthesis. The para-pyridinyl-substituted aryl side chain imparts enhanced solubility and stability under standard coupling conditions. This derivative integrates seamlessly into peptide chains with minimal epimerization risk.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(pyridin-3-yl)phenyl)propanoic acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry. The Fmoc group enables efficient solid-phase peptide coupling, while the phenylpyridine side chain provides a rigid, polar scaffold for drug discovery applications. Its bench-stable nature and compatibility with standard deprotection protocols facilitate reliable incorporation into complex molecular architectures.

General Information

CAS No. 352525-25-8
Cat. No. CS-0169354
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₉H₂₄N₂O₄
Molecular Weight 464.51
Synonym(s) N-Fmoc-4-(3-pyridinyl)-L-phenylalanine
SMILES O=C(O)[C@H](CC1=CC=C(C2=CC=CN=C2)C=C1)NC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O

Computational Chemistry Data

TPSA 88.52
LogP 5.283
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 7

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(pyridin-3-yl)phenyl)propanoic acid

CAS No. 352525-25-8

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