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Structure of 352530-25-7
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This boronate moiety integrates a formyl group and methylthio substituent on a thiophene scaffold, enabling direct functionalization in cross-coupling reactions. The electron-deficient thiophene ring enhances reactivity, while the pendant aldehyde offers downstream derivatization potential. Bench-stable under standard conditions, this reagent streamlines access to complex heterocyclic architectures.
(5-Formyl-4-methylthiophen-2-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its formyl group offers orthogonal reactivity for downstream functionalization, while the boronic acid moiety ensures excellent stability and compatibility with standard Suzuki-Miyaura coupling conditions. The methylthio substituent enhances solubility and facilitates purification, making this reagent well-suited for medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: