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Structure of 352535-97-8
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This boronate moiety features a strategically positioned bromine and fluorine substituent, enabling selective cross-coupling reactions under standard conditions. The ortho-fluorine enhances stability and directs regioselective palladium-catalyzed transformations, while the boronic acid group facilitates efficient Suzuki-Miyaura coupling with minimal protodeboronation.
(3-Bromo-2-fluorophenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki-Miyaura conditions. The ortho-fluoro and bromo substituents provide complementary reactivity for sequential functionalization, while the boronic acid group offers excellent bench stability and ease of purification. Its defined regiochemistry facilitates reliable access to substituted biaryls and heterocyclic scaffolds relevant to pharmaceutical discovery and materials chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: