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CS-W001157 4
Total: USD 88.00

Boc-Cycloleucine

  • CAS No. 35264-09-6

  • Cat. No. CS-W007993
  • Purity≥98%
  • MDL No.MFCD01076126

*For research and further manufacturing use only, not for direct human use.

Boc-Cycloleucine|CS-W007993

Structure of 35264-09-6

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General Information

  • CAS No. 35264-09-6
  • Cat. No. CS-W007993
  • Purity ≥98%
  • MDL No. MFCD01076126
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₄
  • Molecular Weight 229.27
  • Synonym(s) N-Boc-cycloleucine
  • SMILES O=C(C1(NC(OC(C)(C)C)=O)CCCC1)O

Description

Boc-cycloleucine delivers a protected cycloleucine scaffold for peptide synthesis, featuring enhanced stability and compatibility with standard coupling protocols. This bench-stable building block integrates seamlessly into peptidomimetic architectures, enabling efficient access to constrained cyclic motifs in bioactive molecule design.

Application

Boc-cycloleucine serves as a stable, bench-ready building block for the synthesis of cycloleucine-containing peptides and heterocyclic scaffolds. Its tert-butoxycarbonyl group enables straightforward N-terminal protection during solid-phase peptide synthesis, while the cycloleucine core provides conformational rigidity beneficial for structure-activity studies. The derivative exhibits excellent functional group tolerance and facilitates efficient coupling reactions under standard conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.9085
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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