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Structure of 35277-02-2
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4-Fluoro-1H-pyrazole features a fluorinated pyrazole core that imparts enhanced electron-withdrawing character and metabolic stability. This bench-stable heterocycle integrates readily into medicinal chemistry scaffolds, serving as a bioisostere for phenyl or pyridine rings in drug discovery campaigns.
4-Fluoro-1H-pyrazole serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds with enhanced metabolic stability. Its reactive C4 position facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions, while the pyrazole core exhibits good bench stability and compatibility with diverse functional groups. This compound functions effectively in the synthesis of bioactive molecules, particularly in optimizing pharmacokinetic profiles through strategic fluorination.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: