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CS-W001157 4
Total: USD 88.00

Methyl 5-oxopyrrolidine-3-carboxylate

  • CAS No. 35309-35-4

  • Cat. No. CS-W003494
  • Purity≥95%
  • MDL No.MFCD08275678
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Methyl 5-oxopyrrolidine-3-carboxylate|CS-W003494

Structure of 35309-35-4

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Description

Methyl 5-oxopyrrolidine-3-carboxylate is a versatile heterocyclic building block featuring a cyclic amide with a ketone at the C5 position and an ester at C3. This configuration enables direct functionalization at multiple sites, supporting efficient synthesis of pyrrolidine derivatives. The molecule exhibits enhanced stability under standard bench conditions and integrates readily into diverse reaction sequences.

Application

Methyl 5-oxopyrrolidine-3-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to pyrrolidine-based scaffolds through reductive amination and subsequent functionalization. The molecule's α,β-unsaturated lactam moiety facilitates conjugate additions and cycloaddition reactions, while the methyl ester group offers orthogonal handle for selective transformations. Bench-stable and readily purified by flash chromatography, it functions effectively in medicinal chemistry campaigns targeting bioactive heterocycles and peptide mimetics.

General Information

  • CAS No. 35309-35-4
  • Cat. No. CS-W003494
  • Purity ≥95%
  • MDL No. MFCD08275678
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉NO₃
  • Molecular Weight 143.14
  • Synonym(s) Methyl-5-oxopyrrolidin-3-carboxylat
  • SMILES COC(=O)C1CNC(=O)C1

Computational Chemistry Data

  • TPSA   55.4
  • LogP   -0.7045
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501

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