6-Hydroxy-2H-pyran-3(6H)-one

Name: 6-Hydroxy-2H-pyran-3(6H)-one
Brand: ChemScene
Availability: InStock
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CAS No. 35436-57-8
Cat. No. CS-0063151
Purity≥97%
MDL No.MFCD02181121

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

6-Hydroxy-2H-pyran-3(6H)-one features a hydroxylated pyranone core with intrinsic stability under standard conditions. This oxygen-rich scaffold enables direct functionalization at the C6 position, facilitating integration into complex heterocyclic systems. The molecule's polar character supports solubility in protic solvents and enhances compatibility in synthetic transformations requiring controlled reactivity.

Application

6-Hydroxy-2H-pyran-3(6H)-one serves as a versatile scaffold for the synthesis of bioactive heterocycles, leveraging its enolizable hydroxyl and carbonyl functionalities to participate in standard condensation and cyclization reactions. Its bench-stable nature and compatibility with common protecting group strategies facilitate reliable use in multi-step syntheses.

General Information

CAS No. 35436-57-8
Cat. No. CS-0063151
Purity ≥97%
MDL No. MFCD02181121
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₆O₃
Molecular Weight 114.10
Synonym(s) 6-hydroxy-2,3-dihydro-6H-pyrano-3-one
SMILES O=C1COC(O)C=C1

Computational Chemistry Data

TPSA 46.53
LogP -0.5397
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS02
Signal Word : Danger	UN#: 1325
Class : 4.1	Packing Group : Ⅲ
Hazard Statements : H228
Precautionary Statements : P210-P240-P241-P280-P370+P378

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyran compounds

Key Words

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6-Hydroxy-2H-pyran-3(6H)-one

CAS No. 35436-57-8

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