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Structure of 35509-27-4
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Quinoline-8-carbonitrile features a rigid heteroaromatic core with a nitrile group at the 8-position, enabling strong dipole interactions and enhanced solubility in polar solvents. This configuration supports efficient coupling in transition-metal-catalyzed reactions and facilitates incorporation into functionalized materials for optoelectronic applications.
Quinoline-8-carbonitrile serves as a versatile building block in medicinal chemistry and catalysis, enabling direct functionalization at the 8-position via palladium-catalyzed cross-coupling reactions. Its nitrile group provides high stability under standard reaction conditions and facilitates downstream transformations such as amidation or hydrolysis to carboxylic acids. The molecule exhibits excellent bench stability and compatibility with diverse functional groups, making it ideal for modular synthesis of heterocyclic scaffolds and targeted API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: