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CS-W001157 4
Total: USD 88.00

Sulfasuccinamide

  • CAS No. 3563-14-2

  • Cat. No. CS-0203548
  • Molecule weight272.28
  • Purity≥98%
  • MDL No.MFCD00025390

*For research and further manufacturing use only, not for direct human use.

Sulfasuccinamide|CS-0203548

Structure of 3563-14-2

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General Information

  • CAS No. 3563-14-2
  • Cat. No. CS-0203548
  • Purity ≥98%
  • MDL No. MFCD00025390
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂O₅S
  • Molecular Weight 272.28
  • Synonym(s) None
  • SMILES O=C(O)CCC(=O)NC1=CC=C(C=C1)S(=O)(=O)N

Description

4-Oxo-4-((4-sulfamoylphenyl)amino)butanoic acid features a sulfamoyl-substituted phenyl amine linked to a ketone-functionalized aliphatic chain, delivering enhanced solubility and metabolic stability. This scaffold integrates well into bioactive molecule design, particularly in targeted kinase inhibitor frameworks, where the electron-withdrawing sulfamoyl group modulates reactivity and binding affinity.

Application

4-Oxo-4-((4-sulfamoylphenyl)amino)butanoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and peptide conjugates. Its amide-linked sulfamoylphenyl group imparts enhanced solubility and metabolic stability, while the α-keto carboxylic acid moiety enables facile derivatization via nucleophilic addition or condensation reactions. The compound exhibits excellent bench stability and is compatible with standard purification methods, facilitating integration into medicinal chemistry workflows targeting kinase inhibitors and other targeted therapeutics.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   126.56
  • LogP   0.1373
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   5

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