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Structure of 35633-35-3
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1-(2-Methoxy-4-methylphenyl)ethanone features a benzene ring bearing a methoxy group at the ortho position and a methyl substituent at the para position, integrated with a ketone-linked ethyl side chain. This electron-rich aryl ketone serves as a key intermediate in pharmaceutical synthesis, offering enhanced solubility and stability under standard bench conditions.
1-(2-Methoxy-4-methylphenyl)ethanone serves as a versatile aryl ketone building block for medicinal chemistry and process synthesis. Its structure enables direct functionalization at the aromatic ring and compatibility with standard coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig protocols. The methyl and methoxy substituents provide moderate electron-donating character, enhancing reactivity in electrophilic substitution. Bench-stable and readily purified by recrystallization, it functions effectively in multistep syntheses of bioactive scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P405-P501
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Lot numbers can be found on the outside label of a product: