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Structure of 356570-53-1
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This boronate ester features a sterically shielded tetramethyl-1,3,2-dioxaborolane ring paired with a 2,5-dimethylphenyl group, delivering enhanced stability and reactivity in cross-coupling transformations. The electron-rich aryl moiety enables efficient palladium-catalyzed coupling under standard conditions, while the bulky substituents minimize protodeboronation and side reactions. Ideal for constructing complex biaryl architectures with high functional group tolerance.
2-(2,5-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. Its sterically shielded dioxaborolane ring enhances air and moisture tolerance, enabling reliable coupling with aryl halides and triflates under standard conditions. The 2,5-dimethylphenyl group provides a robust, electron-rich aryl handle suitable for constructing complex biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: