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Structure of 35857-90-0
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4,6-Dichloropyridazine-3-carbonitrile features a highly reactive pyridazine core with dual chlorine substituents flanking a nitrile group. This arrangement enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds. The molecule exhibits enhanced electrophilicity at the C4 and C6 positions, promoting selective functionalization under mild conditions.
4,6-Dichloropyridazine-3-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via nucleophilic substitution. The dichloro functionality provides orthogonal reactivity for sequential functionalization, while the carbonitrile group offers compatibility with standard transformations such as amidation or reduction. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for scalable synthesis and parallel library development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: