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CS-W001157 4
Total: USD 88.00

Benzyl chloromethyl ether

  • CAS No. 3587-60-8

  • Cat. No. CS-0015122
  • Purity≥85%
  • MDL No.MFCD00000886

*For research and further manufacturing use only, not for direct human use.

Benzyl chloromethyl ether|CS-0015122

Structure of 3587-60-8

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General Information

  • CAS No. 3587-60-8
  • Cat. No. CS-0015122
  • Purity ≥85%
  • MDL No. MFCD00000886
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉ClO
  • Molecular Weight None
  • Synonym(s) Benzyloxymethyl Chloride
  • SMILES ClCOCC1=CC=CC=C1

Description

Benzyl chloromethyl ether serves as a potent electrophilic alkylating agent, featuring a reactive chloromethyl group tethered to a benzyl moiety. This structure enables efficient functionalization of nucleophiles in synthetic transformations, particularly in peptide modification and carbohydrate chemistry. The compound demonstrates high reactivity under mild conditions, facilitating rapid coupling reactions with amines and thiols. Its stability under standard handling protocols supports reliable use in process development workflows.

Synthesis

  • Route1
    • null|null
      50-00-0
    • In-stock
      Benzyl alcohol|CS-4355
      100-51-6
    • ~95%
    • In-stock
      Benzyl chloromethyl ether|CS-0015122
      3587-60-8

    References

    • Chemistry of Heterocyclic Compounds, , vol. 32, # 3 p. 328 - 332
  • Route2
    • null|null
      110-88-3
    • In-stock
      Benzyl alcohol|CS-4355
      100-51-6
    • ~86%
    • In-stock
      Benzyl chloromethyl ether|CS-0015122
      3587-60-8

    References

    • Journal of the American Chemical Society, , vol. 121, # 43 p. 9967 - 9976
  • Route3
    • null|null
      52132-66-8
    • ~85%
    • In-stock
      Benzyl chloromethyl ether|CS-0015122
      3587-60-8

    References

    • Synthesis, , # 9 p. 762 - 763

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS08
Signal Word : Danger
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H318-H334
Precautionary Statements : P261-P264-P270-P280-P285-P301+P310-P304+P341-P305+P351+P338-P310-P330-P342+P311-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   2.3995
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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