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Structure of 361189-66-4
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Azido-PEG6-acid features a terminal azide group linked to a six-ethylene glycol unit, terminating in a carboxylic acid. This bifunctional scaffold enables site-specific conjugation via copper-catalyzed azide-alkyne cycloaddition while providing solubility and bioorthogonal reactivity. The carboxylic acid facilitates amide coupling or derivatization under standard conditions.
Azido-PEG6-acid serves as a versatile bifunctional linker for bioconjugation and polymer synthesis. The terminal azide group enables reliable copper-catalyzed (CuAAC) or strain-promoted cycloaddition reactions, while the carboxylic acid facilitates amide coupling or activation with reagents like HOBt/EDC. Its six-ethylene glycol units provide excellent solubility and reduced non-specific binding, enhancing performance in aqueous biological environments. This structure offers robust stability, ease of purification, and compatibility with diverse functional groups, making it ideal for constructing site-specific conjugates and modular scaffolds in drug discovery and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: