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CS-W001157 4
Total: USD 88.00

Azido-PEG6-acid

  • CAS No. 361189-66-4

  • Cat. No. CS-0114597
  • Molecule weight379.41
  • Purity≥98%
  • MDL No.MFCD22056306

*For research and further manufacturing use only, not for direct human use.

Azido-PEG6-acid|CS-0114597

Structure of 361189-66-4

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General Information

  • CAS No. 361189-66-4
  • Cat. No. CS-0114597
  • Purity ≥98%
  • MDL No. MFCD22056306
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₉N₃O₈
  • Molecular Weight 379.41
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Description

Azido-PEG6-acid features a terminal azide group linked to a six-ethylene glycol unit, terminating in a carboxylic acid. This bifunctional scaffold enables site-specific conjugation via copper-catalyzed azide-alkyne cycloaddition while providing solubility and bioorthogonal reactivity. The carboxylic acid facilitates amide coupling or derivatization under standard conditions.

Application

Azido-PEG6-acid serves as a versatile bifunctional linker for bioconjugation and polymer synthesis. The terminal azide group enables reliable copper-catalyzed (CuAAC) or strain-promoted cycloaddition reactions, while the carboxylic acid facilitates amide coupling or activation with reagents like HOBt/EDC. Its six-ethylene glycol units provide excellent solubility and reduced non-specific binding, enhancing performance in aqueous biological environments. This structure offers robust stability, ease of purification, and compatibility with diverse functional groups, making it ideal for constructing site-specific conjugates and modular scaffolds in drug discovery and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   141.44
  • LogP   0.871
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   21

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