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Structure of 36127-17-0
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Methyl 8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylate is a rigid, nitrogen-containing bicyclic scaffold featuring a ketone and ester functional group in close spatial proximity. This configuration enables selective reactivity in synthetic transformations, particularly in asymmetric synthesis and medicinal chemistry applications where conformational constraint enhances target binding affinity.
Methyl 8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylate serves as a versatile bicyclic scaffold for medicinal chemistry and synthetic methodology development. Its constrained tricyclic core enables precise stereochemical control, while the ester and ketone functionalities support sequential functionalization. The molecule exhibits bench stability and facilitates efficient derivatization via nucleophilic addition, reduction, or coupling reactions, making it a practical building block in route optimization for complex heterocyclic targets.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: