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CS-W001157 4
Total: USD 88.00

4-Chloro-3H-[1,2,3]triazolo[4,5-c]pyridine

  • CAS No. 36258-82-9

  • Cat. No. CS-W005412
  • Purity≥95%
  • MDL No.MFCD13193520
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Chloro-3H-[1,2,3]triazolo[4,5-c]pyridine|CS-W005412

Structure of 36258-82-9

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Description

4-Chloro-3H-[1,2,3]triazolo[4,5-c]pyridine is a heterocyclic scaffold featuring a chlorinated triazolopyridine core with enhanced electron-deficient character. This rigid, planar structure facilitates π-stacking interactions and integrates readily into bioactive molecules. The chlorine substituent enables site-specific functionalization via palladium-catalyzed coupling reactions, making it valuable for medicinal chemistry and materials synthesis.

Application

4-Chloro-3H-[1,2,3]triazolo[4,5-c]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of triazolopyridine scaffolds. Its chlorine substituent facilitates nucleophilic substitution reactions, supporting the synthesis of diverse analogs through coupling with amines, thiols, and other nucleophiles. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthetic workflows in API development.

General Information

  • CAS No. 36258-82-9
  • Cat. No. CS-W005412
  • Purity ≥95%
  • MDL No. MFCD13193520
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃ClN₄
  • Molecular Weight 154.56
  • Synonym(s) None
  • SMILES ClC1=NC=CC2=C1NN=N2

Computational Chemistry Data

  • TPSA   54.46
  • LogP   1.0063
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

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