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Structure of 362601-71-6
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5-[4-(Trifluoromethyl)phenyl]-1H-pyrazole features a trifluoromethyl-substituted phenyl group attached to the pyrazole core, imparting enhanced electron-withdrawing character and metabolic stability. This configuration supports efficient integration into bioactive scaffolds, particularly in medicinal chemistry campaigns targeting kinase inhibitors and receptor modulators. The compound exhibits robust bench stability and compatibility with standard synthetic transformations.
5-[4-(Trifluoromethyl)phenyl]-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl-substituted aryl group enhances metabolic stability and lipophilicity, while the pyrazole core provides a robust hydrogen-bonding scaffold. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: