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CS-W001157 4
Total: USD 88.00

1-BOC-5-Methyl-3-pyrrolidinone

  • CAS No. 362706-25-0

  • Cat. No. CS-W019809
  • Purity≥98%
  • MDL No.MFCD22376634
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-BOC-5-Methyl-3-pyrrolidinone|CS-W019809

Structure of 362706-25-0

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Description

1-BOC-5-Methyl-3-pyrrolidinone features a protected pyrrolidinone core with a sterically hindered BOC group, enabling stable incorporation into complex molecular architectures. This bench-stable derivative facilitates efficient synthesis of bioactive heterocycles and pharmaceutical intermediates under standard conditions.

Application

1-BOC-5-Methyl-3-pyrrolidinone serves as a versatile pyrrolidinone building block in medicinal chemistry, enabling efficient synthesis of nitrogen-containing heterocycles. The BOC group provides stable protection of the amine functionality under standard reaction conditions, facilitating subsequent transformations such as nucleophilic substitutions and reductive cleavage. Its methyl substituent enhances lipophilicity and structural diversity in target scaffolds, while the cyclic lactam framework supports orthogonal functionalization for complex molecule assembly.

General Information

  • CAS No. 362706-25-0
  • Cat. No. CS-W019809
  • Purity ≥98%
  • MDL No. MFCD22376634
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇NO₃
  • Molecular Weight 199.25
  • Synonym(s) tert-Butyl 2-methyl-4-oxopyrrolidine-1-carboxylate
  • SMILES O=C(N1C(C)CC(C1)=O)OC(C)(C)C

Computational Chemistry Data

  • TPSA   46.61
  • LogP   1.5848
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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