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Structure of 364-74-9
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2,5-Difluoronitrobenzene was used in the synthesis of :N-alkylated 2-arylaminobenzimidazolesquinoxalinonesN-(2-nitro-4-fluorophenyl)-l,2,3,4-tetrahydroisoquinoline
1,4-Difluoro-2-nitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling nucleophilic aromatic substitution (SNAr) reactions under mild conditions. The ortho-fluorine atoms exhibit high reactivity toward amines, thiols, and alcohols, facilitating the construction of complex heterocyclic scaffolds and functionalized aryl linkages. Its bench-stable nature and compatibility with diverse functional groups make it ideal for multi-step synthesis workflows requiring selective transformation and purification.
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GHS Pictogram :
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335-H373
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: