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CS-W001157 4
Total: USD 88.00

2-Chloronicotinaldehyde

  • CAS No. 36404-88-3

  • Cat. No. CS-W008584
  • Molecule weight141.56
  • Purity≥96%
  • MDL No.MFCD01315308

*For research and further manufacturing use only, not for direct human use.

2-Chloronicotinaldehyde|CS-W008584

Structure of 36404-88-3

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General Information

  • CAS No. 36404-88-3
  • Cat. No. CS-W008584
  • Purity ≥96%
  • MDL No. MFCD01315308
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClNO
  • Molecular Weight 141.56
  • Synonym(s) None
  • SMILES O=CC1=CC=CN=C1Cl

Description

2-Chloronicotinaldehyde is a bench-stable, moisture-tolerant aldehyde featuring a chlorine-substituted pyridine ring. This electron-deficient heterocycle integrates readily into cross-coupling and condensation reactions. The para-chloro group enhances reactivity while maintaining structural integrity under standard conditions.

Synthesis

  • Route1
    • null|null
      109-09-1
    • null|null
      68-12-2
    • ~41%
    • In-stock
      2-Chloronicotinaldehyde|CS-W008584
      36404-88-3

    References

    • Jeff Thrasher; Hembre, Erik J.; Gardinier, Kevin M.; Savin, Kenneth A.; Hong, Jian Eric; Jungheim, Louis N. Heterocycles, 2006 , vol. 67, # 2 p. 543 - 547
  • Route2
    • 3-Pyridinecarbonitrile, 2-chloro-|CS-0654103
      6602-54-6
    • ~33%
    • In-stock
      2-Chloronicotinaldehyde|CS-W008584
      36404-88-3

    References

    • New, James S.; Yevich, Joseph P.; Temple, Davis L.; New, Kimberly B.; Gross, Sharon M.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 3 p. 618 - 624
  • Route3
    • null|null
      68-12-2
    • ~%
    • In-stock
      2-Chloronicotinaldehyde|CS-W008584
      36404-88-3

    References

    • WO2004/39807 A1, ; Page 48, 49 ; WO 2004/039807 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H319
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.5475
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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