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Structure of 364077-84-9
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This chiral pyrrolidine derivative features a protected amine and a ketone at the C4 position, enabling direct incorporation into peptide synthesis. The tert-butoxycarbonyl group provides stability and orthogonal deprotection compatibility. This scaffold supports efficient access to bioactive cyclic peptides and constrained peptidomimetics through modular derivatization.
(R)-1-(tert-Butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid serves as a versatile chiral building block in synthetic organic chemistry, enabling the construction of pyrrolidine-based scaffolds prevalent in medicinal chemistry. The protected amine and ketone functionalities offer orthogonal reactivity, facilitating selective transformations and downstream derivatization. Its bench-stable nature and compatibility with standard coupling and reduction protocols make it well-suited for iterative synthesis and scale-up applications.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: