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Structure of 364750-80-1
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This chiral pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and a methyl group at the 4-position, enabling direct incorporation into peptide synthesis. The (2S,4R) stereochemistry ensures high diastereoselectivity in coupling reactions. Bench-stable and moisture-tolerant, it integrates seamlessly into solid-phase and solution-phase workflows for complex peptide assembly.
(2S,4R)-1-(tert-Butoxycarbonyl)-4-methylpyrrolidine-2-carboxylic acid serves as a stereochemically defined building block for the synthesis of peptidomimetics and bioactive heterocycles. The Boc group enables convenient protection and orthogonal deprotection in multi-step sequences, while the 4-methyl substituent enhances conformational rigidity. It functions reliably in standard coupling reactions and facilitates efficient access to constrained scaffolds relevant to medicinal chemistry campaigns.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: