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Structure of 36635-66-2
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a-Tosylbenzyl isocyanide features a tosyl-substituted benzyl group linked to an isocyanide moiety, delivering enhanced stability and solubility in organic media. This combination enables efficient coordination in transition metal catalysis and facilitates the synthesis of complex heterocycles under mild conditions.
a-Tosylbenzyl isocyanide serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions and heterocycle synthesis. Its tosyl-protected benzylic isocyanide functionality enables selective reactivity in Pd- or Ni-catalyzed C–N bond formations, facilitates efficient access to substituted benzimidazoles and triazoles, and offers enhanced bench stability compared to unprotected analogs. The robust tosyl group provides excellent functional group tolerance and simplifies purification in multi-step syntheses.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: