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CS-W001157 4
Total: USD 88.00

a-Tosylbenzyl isocyanide

  • CAS No. 36635-66-2

  • Cat. No. CS-0622113
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

a-Tosylbenzyl isocyanide|CS-0622113

Structure of 36635-66-2

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Description

a-Tosylbenzyl isocyanide features a tosyl-substituted benzyl group linked to an isocyanide moiety, delivering enhanced stability and solubility in organic media. This combination enables efficient coordination in transition metal catalysis and facilitates the synthesis of complex heterocycles under mild conditions.

Application

a-Tosylbenzyl isocyanide serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions and heterocycle synthesis. Its tosyl-protected benzylic isocyanide functionality enables selective reactivity in Pd- or Ni-catalyzed C–N bond formations, facilitates efficient access to substituted benzimidazoles and triazoles, and offers enhanced bench stability compared to unprotected analogs. The robust tosyl group provides excellent functional group tolerance and simplifies purification in multi-step syntheses.

General Information

  • CAS No. 36635-66-2
  • Cat. No. CS-0622113
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₃NO₂S
  • Molecular Weight 271.33
  • Synonym(s) None
  • SMILES CC1=CC=C(C=C1)S(=O)(=O)C(C2=CC=CC=C2)[N+]#[C-]

Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group :
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

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